When the heart contracts, the flaps of the mitral valve fall in to the clip, which is closed then, pinning the edges of the valve flaps jointly at their centers. The result is a bow-tie-formed starting that permits blood flow from the remaining atrium to the left ventricle during relaxation of the heart, and allows the valve flaps to close more effectively during contraction, than allowing leakage of blood backward into the left atrium rather. The EVEREST I research, which was conducted to evaluate the basic safety and feasibility of the MitraClip, recruited 55 individuals with moderate-to severe mitral symptoms and regurgitation such as fatigue and shortness of breath with exercise.Related StoriesResilience-based programs can help LGBT youths cope with negative stressorsResearchers determine potential brain-centered biomarker for depressive symptomsReducing depressive disorder to a checklist of symptoms may not be useful, new research revealsLuk’s study was funded by Eunice Kennedy Shriver National Institute of Kid Health and Human Advancement . Drs. Jing Wang and Bruce Simons-Morton, both at NICHD, were co-authors and Luk’s mentors for the analysis. It was based on data on bullying from the 2005/2006 U.S. Health Behavior in School-aged Children . Luk analyzed that data even though he was on a scholarly study program at NICHD.