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National Depressive disorder Initiative beyondblue estimates that at least one in five Australians will encounter despair or another mental disease during their lives. Researchers analysed job stress data gathered from a 2003 survey of 1100 Victorian workers. Associate Professor LaMontagne said women and those in lower-skilled occupations will experience job stress, therefore bear a greater share of work stress-related depression. Associate Professor LaMontagne said that solutions are available to address this issue.. Almost 1 in 6 cases of depression among operating Victorians are due to job stress Almost one in six cases of depression among functioning Victorians are due to job stress.The composite of cardiovascular loss of life, myocardial infarction, stroke, or urgent coronary revascularization became the main secondary end stage. Definitions of the components of these composite end points are given in the Supplementary Appendix. We assessed bleeding using the Global Use of Strategies to Open Occluded Coronary Arteries classification system and the TIMI classification system, with GUSTO severe or moderate bleeding thought as the safety end point of primary interest. A clinical-occasions committee whose members were unaware of the study-group assignments adjudicated all components of the primary and major secondary efficacy end factors and bleeding episodes. Statistical Analysis We calculated that 2279 events would be required to provide a power of at least 90 percent to detect a 15 percent relative risk decrease in the composite end point of cardiovascular loss of life, myocardial infarction, stroke, or urgent coronary revascularization in the vorapaxar group, as compared with the placebo group.